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Product Catalogue

​Immune Globulin, Pooled

Transfusion Medicine

​Alternate Product Names
  • ​Intravenous Immune Globulin (IVIG)
    • Gammagard S/D 
    • Gammagard liquid
    • Gammunex
    • IGIVnex
    • Privigen
  • Subcutaneous Immune Globulin (SCIG)
    • Cuvitru
​Indications
  • ​Immunology:
    • Primary Immune Deficiency
    • Acquired (Secondary) Hypogammaglobulinemia
    • Advanced, complicated HIV
    • Acute antibody mediated rejection (AMR) following organ transplant 
    • Sensitized organ transplant recipient
    • Steroid resistant rejection in organ transplantation
  • Hematology:
    • Acute idiopathic thrombocytopenic purpura (ITP) with bleeding
    • Steroid-refractory ITP
    • Post transfusion purpura (PTP)
    • HIV and refractory thrombocytopenia
    • Neonatal alloimmune thrombocytopenia (NAIT)
    • Parvovirus pure red cell aplasia (PRCA) in immunocompromised patient
    • Serious Hemolytic transfusion reactions (HTR)/Hemolytic disease of the newborn (HDN)
  • Neurology:
    • Guillain-Barré syndrome (GBS)
    • Chronic idiopathic demyelinating polyneuropathy (CIDP)
    • Multifocal motor neuropathy
  • Rheumatology:
    • Dermatomyositis
    • Kawasaki disease
  • Dermatology:
    • Pemphigus vulgaris, if steroid refractory
    • Staphylococcus toxic shock, with or without fasciitis
​Resource Information

Product Monographs:

Intravenous Immune Globulin (IVIG)

Subcutaneous Immune Globulin (SCIG)
Size/Volume Available
  • 2.5 g, 5 g, 10 g, 20 g, 30 g
    • size availability from each manufacturer varies
Availability

​Product Size
​Saskatoon​Rural
2.5 gm​YesContact your site laboratory​ ​ ​ ​ ​
​5 g
​Yes
​10 g
​Yes
​20 g
​Yes
​30 g
​Yes
  • ​Rural (Humboldt, Lanigan, Rosthern, Wadena, Watrous, Wynyard): ordered as needed
Pretransfusion Testing Requirements
  • ​ABO Group and Rh is recommended prior to the first IVIg infusion
Forms Required

​Saskatoon:

Rural

  • Contact your site laboratory
Ordering
  • Indicate:
    • Recipient weight (kg) and diagnosis
    • Dosage in grams
  • Special requirements by physician must be indicated
  • Name and contact information of ordering physician is required
​Notes
  • IVIG dosage should be requested based on ideal body weight calculation
  • ​Gammagard S/D is issued only if there is  suspicion of recipient IgA deficiency (confirmation of anti-IgA antibody presence is strongly encouraged)
  • Risk of delayed hemolytic transfusion reaction due to the presence of anti-A or anti-B antibodies is uncommon, but possible (risk~1:1000 non-Group O recipients of IVIG)
    • Evaluation of patient hemoglobin level 7 days following IVIG infusion in a non-Group O recipient is recommended
    • A drop in hemoglobin of greater than 10g/L post-IVIG infusion should be reported as a transfusion reaction
  • A Transfusion Medicine/Canadian Blood Services chart report is NOT required for product infusion

  • For Subcutaneous Immune Globulin (SCIG) home infusion:
​Administration

 

​If you choose to print this information, it is valid only on date of print.

Laboratory Controlled Document LSM-62 v7

Last Modified: Thursday, February 7, 2019 |
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