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Product Catalogue

​Plasma

Transfusion Medicine

​Alternate Product Names
  • ​FP
  • FFP
  • Fresh Frozen Plasma
  • Frozen Plasma
​Indications
  • ​Bleeding or prior to a significant operative procedure in patients with multi-coagulation factor deficiency when no coagulation factor concentrates or alternative therapies are appropriate or available. (i.e. liver disease, DIC)
    • INR greater than or equal to 1.7 and increased PTT
  • Single factor deficiencies for which no concentrate is available (i.e. Factor V)
  • Massive transfusion
  • Therapeutic Plasma Exchange in Thrombotic Thrombocytopenia Purpura (TTP), if cryosupernatant plasma is unavailable
  • Urgent warfarin reversal in patients experiencing major bleeding or requiring urgent surgery if there is a contraindication to prothrombin complex concentrates (PCC), or if PCC are unavailable 
  • Plasma transfusion is NOT appropriate in the following situations:
    • As a volume expander or nutritional supplement
    • Treatment of factor deficiency if recombinant or plasma derived, virally inactivated products are available
    • Treatment of an isolated high INR in the setting of liver failure prior to procedure
    • Treatment of a mildly elevated INR (less than 1.8) for any reason prior to procedure or in the setting of bleeding
    • Elevated INR at any value, in the absence of bleeding
    • Warfarin reversal, if PCC is available
    • Reversal of heparin, LMWH, direct factor II inhibitor, or direct factor Xa inhibitor
​Resource Information
Size/Volume Available
  • Volume indicated on unit
Availability
​RUH​SCH​SPH​Rural
​Yes​YesYesYes
​Note: Other rural locations - consult with your laboratory
Pretransfusion Testing Requirements
  • ​ABO Group and Rh Type on current admission
    • Contact Transfusion Medicine/lab prior to collection to confirm
Forms Required

​Saskatoon/Humboldt:

Rural:

  • Contact your site laboratory
Ordering
  • Routine Transfusion
    • Indicate number of units required (standard dose is 10-15 mL/kg)
      • For pediatric/neonate transfusion indicate volume of plasma in mLs
    • Indicate diagnosis
    • Indicate urgency 
    • Time/date to be transfused
    • For surgery, including surgical date 
  • Therapeutic plasma exchange
  • Massive Transfusion Protocol (MTP)
    • Four units included within each massive transfusion protocol box
  • Allow approximately 30 minutes for product to be thawed
​Notes
  • Rh compatibility not required
  • Frozen Plasma (FP) and Fresh Frozen Plasma (FFP) are considered equivalent in terms of clinical efficacy
    • Issue of FP versus FFP units will be an inventory management decision by the Transfusion Medicine Laboratory
  • Plasma volume indicated on lower left corner of product label
  • Plasma shall be issued one unit at a time depending on the clinical situation (exception – during a MTP activation)
  • Do not send for product prior to obtaining patient’s informed consent being obtained or line placement
  • Patients who have repeated allergic-type reactions or a severe transfusion adverse event with plasma transfusion may be eligible to receive solvent-detergent plasma (Transfusion Medicine Physician approval is required for S/D plasma)
​Administration

 

​If you choose to print this information, it is valid only on date of print.

Laboratory Controlled Document LSM-63 V4

Last Modified: Friday, September 8, 2017 |
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