• ​Replacement of plasma coagulation factors or specific plasma proteins in patients who require a high volume of transfusions annually with a diagnosis of:
• Thrombotic thrombocytopenic purpura (TTP), congenital or acquired, or
• Hemolytic uremic syndrome (HUS) with associated factor H deficiency, or
• Clotting factor deficiencies for which specific licenced concentrate may not be readily available ( e.g. factor V, Factor XI, factor XIII)

AND

• Meet one of the following secondary qualifiers, including those who:
• Have experienced an allergic reaction to frozen plasma, or
• Have a pre-existing lung disorder, or
• Need frozen plasma but a blood group compatible product is not available in a timely manner