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Product Catalogue

​Platelets

Transfusion Medicine

​Alternate Product Names
  • ​Apheresis platelets (single-donor platelets)
  • Buffy-coat platelets (pooled platelets)
  • PLT
  • Platelet concentrate (PLC)
​Indications
  • ​Thrombocytopenia and bleeding prophylaxis:
    • Platelet less than or equal to 10 x 109/L for prophylaxis in hypoproliferative thrombocytopenia
    • Platelet less than 30 x 109/L for elective central venous catheter placement of minor elective procedures
    • Platelet less than 50 x 109/L for lumbar puncture or major elective non-neuraxial surgery
    • Platelet less than 100 x 109/L for neurosurgical
  • Bleeding patient to treat clinically significant bleeding in the setting of thrombocytopenia
  • Bleeding of any level with platelet dysfunction (congenital or medication-induced)
  • Massive transfusion protocol
​Resource Information
Size/Volume Available
  • Approximately 300 mL
  • Volume indicated on product label
Availability
​RUH​SCH​SPH​Rural
​Yes​No*​Yes**​No
  • ​*SCH requests will be transported from RUH as requests are received
  • **SPH regular stock includes only one unit, additional units will be transported from RUH as requests are received
  • Rural: Humboldt, Lanigan, Rosthern, Wadena, Watrous, Wynyard - ordered as needed from Canadian Blood Services, Regina
Pretransfusion Testing Requirements
  • ​ABO Group and Rh Type on current admission
    • Contact Transfusion Medicine/lab prior to collection to confirm testing for chronically transfused patients
Forms Required

​Saskatoon:

Rural:

  • Contact your site laboratory
Ordering
  • Indicate:
    • Volume of platelets required
      • Adult transfusion: number of adult doses required (1 adult dose = 1 apheresis platelet or 1 pooled platelet)
      • Pediatric/neonate transfusion: total mL volume required until volume equals that of one average platelet unit (300-350mL), then order an adult dose of platelets
    • Number of adult doses required (1 adult dose = 1 apheresis platelet or 1 pooled platelet)
    • Need for transfusion: time and date of planned transfusion, on hold, or for surgery (surgical date indicated)
    • Special requirements must be included, if required, as directed by a physician:
      • Irradiated
      • HLA-matched (with proven platelet refractoriness due to HLA antibodies)
      • HPA-matched (suspected or proven HPA antibodies causing Neonatal Alloimmune Thrombocytopenia (NAIT) or Post-Transfusion Purpura (PTP))
      • Washed (with a history of severe, recurrent allergic reaction resistant to medical therapy)
  • A pre-transfusion platelet count must be available demonstrating thrombocytopenia before platelet issue, with the exception of the platelet included in the first box of a Massive Transfusion Protocol
  • Only one unit of platelets will be issued at a time from the Transfusion Medicine Lab, unless approval of the on-call Transfusion Medicine Physician is obtained
​Notes
  • ​All platelets are pre-storage leukoreduced
  • If platelet alloimmunization is suspected, a 1 hour post-transfusion platelet count that demonstrates a poor platelet increment  on two separate occasions is strongly recommended  before testing for HLA antibodies will be pursued
    • Contact the contact the Transfusion Medicine Physician to discuss approval for local HLA antibody testing
  • HLA antigen matched platelets may be requested for patients with proven HLA-alloimmunization
  • HPA antigen negative platelets may be requested for patients with suspected or proven HPA antibodies causing NAIT or PTP
    • Contact the Transfusion Medicine Physician to discuss individual cases
    • Saskatoon - Lab use only: complete FORM-418
  • In order to prevent the formation of Anti-D, Rh immunoglobulin will be recommended for Rh negative patients who receive Rh positive platelets
  • A post-transfusion platelet count is recommended within 1 hour of transfusion following each dose administered to ensure appropriate post-transfusion increment (based on a calculated corrected count increment (CCI) or increase of approximately 15-20 x 109/L, at minimum)
​Administration
  • ​Physician order requires a rate (or duration) for transfusion, according to the Blood Administration Policy
  • Administration information can be found in the Nursing Policy and Procedure Manual #1141
  • Contains human protein; informed patient consent required for this product
  • Must be transfused within 4 hours of issue
  • If transfusion is no longer needed, return to the Transfusion Medicine with 60 minutes of issue

 

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Laboratory Controlled Document LSM-64 v4

Last Modified: Friday, June 1, 2018 |
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