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Pathology and Laboratory Medicine
Test Catalogue

​Medical Renal Biopsy

Histology - Anatomic Pathology

Specimen Requirements​ ​

​Container
  • Leak-proof specimen container
​Collection Procedure
  • ​Renal biopsies must be booked in advance to ensure technologists are available to process the specimen.  Call 655-8569. You will need patient’s name, date and time of collection and hospital where the specimen will be procured.
  • If biopsy is cancelled, please call 655-8569
  • Label container with patient’s first and last name, personal health number (PHN)
  • The removed biopsy should be placed on saline soaked gauze (or Telfa™ pads soaked with Normal Saline) in leak-proof labelled specimen container. Fold the gauze or Telfa™ pad over the biopsy pieces to avoid drying of the specimen. Please avoid filling the container with liquid of any sort (saline, RPMI, etc.); this causes the biopsy pieces floating inside the container and may subsequently lead to loss of tissue and considerable processing artifacts.
  • Place specimen container in a plastic bag containing crushed ice
  • Complete a Surgical Pathology Requisition Form #4030 with the patient’s addressograph, site of biopsy, all relevant clinical history and physician’s signature
  • Baseline biopsies sent in formalin can be shipped directly to the SCH Histology laboratory, room #5522

Deliver as follows:

  • RUH 0800 – 1530 h:
    • Phone laboratory porter (306) 221-6376 to request STAT delivery to RUH Histology laboratory room #2854
    • Call RUH Histology laboratory (2155) to inform them that a fresh renal biopsy is enroute
    • Phone 655-8569 to inform Histology technologist that biopsy is enroute
  • RUH – Specimens retrieved outside of 0800 - 1530 h:
    • Phone TForce Final mile courier (formerly Dynamex) at (306) 975-1010 to request STAT delivery to SCH Histology laboratory room #5522
    • Phone 655-8569 to inform Histology technologist that biopsy is enroute
  • SPH:
    • Deliver to Specimen Management laboratory – B wing – level 1 and indicate STAT renal biopsy to be sent to SCH Histology laboratory room #5522
    • Phone 655-8569 to inform Histology technologist that biopsy is enroute
  • SCH:
    • Deliver to SCH Histology laboratory room #5522
    • Phone 655-8569 to inform Histology technologist that biopsy is enroute
​Stability/Storage
  • ​Transport on ice
​Grounds for Rejection

Testing Information​ ​

​Availability
  • ​Monday to Friday (excluding statutory holidays), 0630-1600 h
  • STAT testing is available on call back basis as required. Must be approved by pathologist-on-call.
​Testing Site
  • ​SCH
​Specimen Retention
  • Specimen which has been submitted for paraffin processing will be maintained as per CPSS Retention Guidelines (i.e. Specimens from patients 0-17 years retained for 50 years; specimens from patients 18 years and older retained for 20 years)
  • Formalin fixed unprocessed tissue retained for 8 weeks following sign out by a pathologist
​Alternate Test Names
  • ​Kidney biopsy

Test Ordering Requirements​ ​

​Forms Required

Patient History​ ​

​Relevant Clinical History
  • Urinalysis results (i.e. presence and quantity of protein; blood; amount and type of casts)
  • Renal function test (BUN and creatinine) and time frame of changes
  • Results of serology
  • Radiographic findings (symmetry, obstruction, etc)
  • For transplants: Duration of transplant, pre-transplant diagnosis, donor information (living, deceased, related, etc.), polyoma serology (if done), history of prior transplants, relevant interventions (i.e. changes in immunosuppressive therapy), reasons for biopsy, serum levels of immunosuppressive therapy
​Relevant Recent Medication History
  • ​Analgesics
  • Penicillamine
  • Hydralazine
  • Chemotherapeutic agents
  • Antihypertensives
  • ACE inhibitors
  • Angiotensin receptor blockers


​If you choose to print this information, it is valid only on date of print.

Laboratory Controlled Document LSM-330 v3

Last Modified: Monday, March 11, 2019 |
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