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Pathology and Laboratory Medicine
Test Catalogue

​Uroporphyrinogen Decarboxylase (UPG D), Whole Blood


​Ordering Recommendation

  • ​ ​Patient should abstain from alcohol for 24 hours

​ ​Specimen Requirements

  • ​Whole blood
​Collection Procedure
  • ​Immediately place specimen on wet ice; keep specimen cool
​Required Volume
  • ​Optimal Volume: 4.5 mL Full collection tube
  • Minimum Volume: 3.0 mL
    (Submitting the minimum volume makes it impossible to repeat the test or perform confirmatory/reflex testing. In some situations, a minimum volume may require a second collection.)
​Stability/ Storage
  • ​Keep specimen cool as soon as collected (wet ice, see above) and during shipping
  • Specimen stable for 7 days
Grounds for Rejection​

Testing Information​ ​

  • ​Shipped weekly on Tuesdays
Testing Site​
  • ​Referred out by St. Paul’s Hospital Laboratory
Results Reporting​
  • Three days turn around time by testing laboratory
Clinical Interpretation
  • ​Diagnosis of porphyria cutanea tarda type II and hepatoerythropoietic porphyria
​Alternate Test Names
  • ​UPG D
SHR LIS Test Code​
  • ​UPDC (For Laboratory Use Only)

Patient History​ ​

​Relevant Clinical History
  • ​The workup of patients with a suspected porphyria is most effective when following a stepwise approach
  • See Porphyria (Cutaneous) Testing Algorithm in Special Instructions or contact Mayo Medical Laboratories to discuss testing strategies
​Relevant Recent Medication History
  • ​Abstinence from alcohol for at least 24 hours is essential, as alcohol suppresses enzyme activity for 24 hours after ingestion. Ingestion may lead to a false-positive result


​If you choose to print this information, it is valid only on date of print.

Laboratory Controlled Document LSM-767 v2

Last Modified: Wednesday, February 17, 2016 |
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